The offline DFC tablet dissolution systems include a fraction collector or an auto sampler which will collect the sampled dissolution media. The semi-automated DFC-820SP system is composed of a PTWS 820D staggered stirrer start dissolution bath with built-in individual vessel centering, full tubing installation in PTFE including either in-situ sampling probes or the EPE-820 auto sampling system, a PT-SP8 syringe pump, and a PTFC-2/8SP fraction collector. In this configuration the sampling probes are either always immersed into the media (in-situ) or removed after sampling (EPE-820 system). Both procedures are widely used.
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